Which lobe of the cerebrum is involved in interpretation and understanding of speech?

The temporal lobe is primarily responsible for the interpretation and understanding of speech. This lobe contains key areas such as Wernicke's area, which is crucial for language comprehension. Damage to this region can result in difficulty in understanding spoken words, highlighting its importance in processing auditory information and facilitating meaningful communication.

The frontal lobe is mainly associated with higher cognitive functions, including decision-making, planning, and voluntary movement, while the parietal lobe is involved in processing sensory information from the environment and spatial awareness. The occipital lobe is primarily focused on visual processing. Each of these lobes has specialized functions, but the temporal lobe stands out for its critical role in language comprehension, making it the correct answer for this question.